Sigman, Caroline C: search on Z-Library

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1

Preclinical efficacy evaluation of potential chemopreventive agents in animal carcinogenesis models: Methods and results from the NCI chemoprevention drug development program

Vernon E. Steele, Richard C. Moon, Ronald A. Lubet, Clinton J. Grubbs, Bandaru S. Reddy, Michael Wargovich, David L. McCormick, Michael A. Pereira, James A. Crowell, Donya Bagheri, Caroline C. Sigman,

Journal:

Journal of Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 1.86 MB

english, 1994

2

Cancer biomarkers: selecting the right drug for the right patient

Kelloff, Gary J., Sigman, Caroline C.

Journal:

Nature Reviews Drug Discovery

Year:

2012

Language:

english

File:

PDF, 528 KB

english, 2012

3

New agents for cancer chemoprevention

Gary J. Keiloff, Charles W. Boone, James A. Crowell, Vernon E. Steele, Ronald A. Lubet, Linda A. Doody, Winfred F. Malone, Ernest T. Hawk, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 3.10 MB

english, 1996

4

New science-based endpoints to accelerate oncology drug development

Gary J. Kelloff, Caroline C. Sigman

Journal:

European Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 157 KB

english, 2005

5

Use of in vitro assays to predict the efficacy of chemopreventive agents in whole animals

Dr. Vernon E. Steele, Sheela Sharma, Rajendra Mehta, Eugene Elmore, J. Leslie Redpath, Colette Rudd, Donya Bagheri, Caroline C. Sigman, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 1.46 MB

english, 1996

6

Biomarker development in the context of urologic cancers

Kelloff, Gary J., Sigman, Caroline C., Scher, Howard I.

Journal:

Urologic Oncology: Seminars and Original Investigations

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015

7

Preclinical Efficacy Studies of Green and Black Tea Extracts

Vernon E. Steele, Donya Bagheri, Douglas A. Balentine, Charles W. Boone, Rajendra Mehta, Mark A. Morse, Sheela Sharma, Caroline C. Sigman, Gary D. Stoner, Michael J. Wargovich, John H. Weisburger, Son

Journal:

Proceedings of The Society for Experimental Biology and Medicine

Year:

1999

Language:

english

File:

PDF, 21 KB

english, 1999

8

Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam

Moon, Richard C., Kelloff, Gary J., Detrisac, Carol J., Steele, Vernon E., Thomas, Cathy F., Sigman, Caroline C.

Journal:

Year:

1993

Language:

english

File:

PDF, 322 KB

english, 1993

9

Rationale for the selection and use of in vitro assays to screen for chemopreventive agents

Vernon E. Steele, Charles W. Boone, Ronald A. Lubet, Caroline S. Sigman, Gary J. Kelloff

Journal:

Methods in Cell Science

Year:

1997

Language:

english

File:

PDF, 11 KB

english, 1997

10

Database of inhibitors of carcinogenesis a

Bagheri, Donya, Doeltz, Mary K., Fay, Judith R., Helnes, C. Tucker, Monasmith, Lori A., Sigman, Caroline C.

Journal:

Environmental Carcinogenesis Reviews

Year:

1988

Language:

english

File:

PDF, 499 KB

english, 1988

11

Clinical development of estrogen modulators for breast cancer chemoprevention in premenopausal vs. postmenopausal women

Julia A. Lawrence, Phyllis B. Malpas, Caroline C. Sigman, Gary J. Kelloff

Journal:

Journal of Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

12

A Systematic Search for Structure-Activity Relationships of Skin Contact Sensitizers: Methodology.

Benezra, Claude, Sigman, Caroline C., Perry, Linda R., Helmes, C. Tucker, Maibach, Howard I.

Journal:

The Journal of Investigative Dermatology

Year:

1985

File:

PDF, 2.14 MB

1985

13

Development of Breast Cancer Chemopreventive Drugs

Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

The Breast Journal

Year:

1995

Language:

english

File:

PDF, 1.35 MB

english, 1995

14

Assessing intraepithelial neoplasia and drug safety in cancer-preventive drug development

Kelloff, Gary J., Sigman, Caroline C.

Journal:

Nature Reviews Cancer

Year:

2007

Language:

english

File:

PDF, 423 KB

english, 2007

15

PRECLINICAL DRUG DEVELOPMENT PARADIGMS FOR CHEMOPREVENTIVES

Steele, Vernon E., Boone, Charles W., Lubet, Ronald A., Crowell, James A., Holmes, Cathy A., Sigman, Caroline C., Kelloff, Gary J.

Journal:

Hematology/Oncology Clinics of North America

Year:

1998

Language:

english

File:

PDF, 1.12 MB

english, 1998

16

The Role of Minimal Residual Disease Testing in Myeloma Treatment Selection and Drug Development: Current Value and Future Applications

Anderson, Kenneth C., Auclair, Daniel, Kelloff, Gary J., Sigman, Caroline C, Avet-Loiseau, Herve, Farrell, Ann T., Gormley, Nicole J., Kumar, Shaji K., Landgren, Ola, Munshi, Nikhil C., Cavo, Michele,

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

17

Potential use of lipoxygenase inhibitors for cancer chemoprevention

Steele, Vernon E, Holmes, Cathy A, Hawk, Ernest T, Kopelovich, Levy, Lubet, Ronald A, Crowell, James A, Sigman, Caroline C, Kelloff, Gary J

Journal:

Expert Opinion on Investigational Drugs

Year:

2000

Language:

english

File:

PDF, 162 KB

english, 2000

18

Cancer Chemoprevention || Tea Polyphenols as Cancer Chemopreventive Agents

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2004

Language:

english

File:

PDF, 2.53 MB

english, 2004

19

Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation

Keating, Susan M., Taylor, D. Lansing, Plant, Anne L., Litwack, E. David, Kuhn, Peter, Greenspan, Emily J., Hartshorn, Christopher M., Sigman, Caroline C., Kelloff, Gary J., Chang, David D., Friberg,

Journal:

Clinical and Translational Science

Year:

2018

Language:

english

File:

PDF, 743 KB

english, 2018

20

Fenretinide: a prototype cancer prevention drug

Malone, Winfred, Perloff, Marjorie, Crowell, James, Sigman, Caroline, Higley, Howard

Journal:

Expert Opinion on Investigational Drugs

Year:

2003

Language:

english

File:

PDF, 163 KB

english, 2003

21

Strategies for phase II cancer chemoprevention trials: Cervix, endometrium, and ovary

Dr. Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 782 KB

english, 1995

22

Cancer Chemoprevention || Antiinflammatories and Chemoprevention

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2004

Language:

english

File:

PDF, 3.55 MB

english, 2004

23

Agents, biomarkers, and cohorts for chemopreventive agent development in prostate cancer

Gary J Kelloff, Ronald Lieberman, Vernon E Steele, Charles W Boone, Ronald A Lubet, Levy Kopelovich, Winfred A Malone, James A Crowell, Howard R Higley, Caroline C Sigman

Journal:

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

24

Synthesis, chemical characterization, and mutagenic activities of promutagens produced by pyrolysis of proteinaceous substances

John H. Peters, Kristien E. Mortelmans, Elmer J. Reist, Caroline C. Sigman, Ronald J. Spanggord, David W. Thomas

Journal:

Environmental and Molecular Mutagenesis

Year:

1981

Language:

english

File:

PDF, 565 KB

english, 1981

25

Mapping cyclic AMP binding sites on type I and type II cyclic AMP-dependent protein kinases using 2-substituted derivatives of cyclic AMP

Terry S. Yagura, Caroline C. Sigman, Pricilla A. Sturm, Elmer J. Reist, Howard L. Johnson, Jon P. Miller

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 396 KB

english, 1980

26

Cancer Chemoprevention || Antigenotoxic and Cancer Preventive Mechanisms of N-Acetyl-l-Cysteine

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2004

Language:

english

File:

PDF, 6.55 MB

english, 2004

27

Chemoprevention of Prostate Cancer: Concepts and Strategies

Kelloff, Gary J., Lieberman, Ronald, Steele, Vernon E., Boone, Charles W., Lubet, Ronald A., Kopelovitch, Levy, Malone, Winfred A., Crowell, James A., Sigman, Caroline C.

Journal:

European Urology

Year:

1999

Language:

english

File:

PDF, 248 KB

english, 1999

28

Cancer Chemoprevention || The Role of Phytoestrogens as Cancer Prevention Agents

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2004

Language:

english

File:

PDF, 2.04 MB

english, 2004

29

Cancer Chemoprevention ||

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2004

Language:

english

File:

PDF, 119.68 MB

english, 2004

30

Cancer Chemoprevention || Preclinical Animal Models for the Development of Cancer Chemoprevention Drugs

Kelloff, Gary J., Hawk, Ernest T., Sigman, Caroline C.

Year:

2005

Language:

english

File:

PDF, 228 KB

english, 2005

31

Development of new cancer chemoprevention agents: role of pharmacokinetic/pharmacodynamic and intermediate endpoint biomarker monitoring

Lieberman, Ronald, Crowell, James A, Hawk, Ernest T, Boone, Charles W, Sigman, Caroline C, Kelloff, Gary J

Journal:

Clinical Chemistry

Year:

1998

File:

PDF, 383 KB

1998

32

Mechanistic considerations in chemopreventive drug development

Dr. Gary J. Kelloff, Charles W. Boone, Vernon E. Steele, Judith R. Fay, Ronald A. Lubet, James A. Crowell, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Year:

1994

Language:

english

File:

PDF, 2.39 MB

english, 1994

33

Risk biomarkers and current strategies for cancer chemoprevention

Gary J. Kelloff, Charles W. Boone, James A. Crowell, Susan G. Nayfield, Ernest Hawk, Winfred F. Malone, Vernon E. Steele, Ronald A. Lubet, Caroline C. Sigman

Journal:

Journal of Cellular Biochemistry

Year:

1996

Language:

english

File:

PDF, 1.28 MB

english, 1996

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